Cooperative activation is critical for the applications of synthetic biology in mammalian cells.In this study, we have developed cooperative transcription factor by fusing oligomerization domain in mammalian cells.Firstly, we demonstrated that two oligomerized domains (CI434 and CI) successfully improved transcription factor cooperativity in bacter

The article describes the clinical case of a difficult systemic juvenile arthritis refractory to Tape traditional immunosuppressant and TNF blocker therapy.The disease was characterized by such extra-articulate manifestations as fever, lymphadenopathy, hepatolienomegaly, polyorrhymenitis, generalized joint affection and high laboratory activity ind

Penentuan rute armada merupakan salah satu permasalahan optimisasi kombinatorik yang memiliki pengaruh pada distribusi barang.Pengiriman barang cepat busuk (perishable good) seperti produk darah, dengan karakteristik jarak tempuh yang Roller Wheel pendek memungkinkan untuk dilakukan dengan satu kendaraan.Terdapat kendala time windows pada pelanggan

It is demonstrated numerically that a metamaterial-inspired, low profile (height approximately λ/80), electrically small (ka = 0.45) Huygens source antenna can be designed to radiate at 300 MHz in its broadside direction with a high radiation efficiency and a large front-to-back ratio.Two electrically small, near-field resonant parasitic (NF